The Second Affiliated Hospital of Hainan Medical University was founded in 1952, have general hospital, Donghu Branch and Wushi Branch , cover over an area of 456,000 square meters. The total number of beds in the General Hospital is 2,603, with 2,674 employees, including 2,218 professional and technical personnel, 298 with deputy and above titles, and 272 with postgraduate degree, 2 doctoral supervisors and 37 master supervisors. At present, there are 59 clinical departments, 12 medical technology departments, 2 provincial medical center, 1 provincial clinical medical research center，1 hospital in a hospital and 1 research institute. It has national organ transplant qualification, the designated hospital for test-tube baby in Hainan Province, the network hospital of international emergency rescue center, and the national emergency medical rescue Base (Hainan) and National Maritime Emergency Medical Rescue Base (Hainan), International "Smile Train" designated hospital, National Health Commission Peritoneal Dialysis Demonstration Center Cultivation Unit, National Resident Standardized Training Base, National Drug Clinical Trial Institution, National Training Base for Clinical Pharmacist and the Council Member of the The Belt and Road tropical medical alliance.

海南医学院第二附属医院始建于1952年，医院现分总院、东湖分院和乌石分院三个院区，占地面积684亩，实际开放床位2603张。医院职工2674人，其中专业技术人员2218人，副高及以上职称298人，博硕士研究生272人,博导2人，硕导37人。现有59个临床科室、12个医技科室，2个省级医学中心，1个省级临床医学研究中心，1个院中院，1个研究所。具有国家器官移植资质，是海南省“试管婴儿”定点医院、国际紧急救援中心网络医院、国家紧急医学救援（海南）基地和国家海上紧急医学救援(海南）基地医院、国际“微笑列车”定点医院、国家卫生与健康委员会腹膜透析示范中心培育单位、国家住院医师规范化培训基地、国家药物临床试验机构、国家临床药师培训基地和一带一路国家热带医学联盟理事单位。